Enable JavaScript to run this app.
Skip to main content
OpenTable logo
The Perfect Place to Fall in Love - Chemistry, Chicago, IL

Chemistry

4.6 (2450)
$31 to $50
American
5121 S Harper Ave, Chicago, IL 60615

Make a reservation

A photo of Chemistry restaurant

Chemistry

4.6
$31 to $50
American
Hyde Park

Make a reservation

2 people
7:00 PM
Booked 62 times today

About this restaurant

  • Good for special occasions
  • Lively
  • Great for creative cocktails
Located in Chicago's Hyde Park neighborhood, Chemistry is Chicago's premier Black-owned Steakhouse! Enjoy the most delicious steak while experiencing excellent white-glove service. Chemistry exemplifies black excellence at its finest.

When the creator of Chemistry first started dating, he wondered "If there were only a place that was breathtaking upon entry, amazing live bands and DJ's, delicious photographable food, good service, along with a place to get up and dance," he’d show up as much as his pockets could afford. However that place didn’t exist, until now. Chemistry, the perfect mix of a high-end late-night steakhouse, booming brunch spot, and tantalizing nightlife vibes all created to be the perfect place to experience love!

*Large Parties over 12 are unable to make an online reservation. Please email your request to reservations@chemistrychicago.com

Please note: We are a Cashless Establishment. We are not open for dinner service on Friday nights

Dining areas

Additional information

  • Dining style
    Casual Dining
  • Price
    $31 to $50
  • Cuisines
    American
  • Hours of operation
    Mon, Tue, Thu 6:00 pm–10:30 pm Wed 6:30 pm–8:30 pm Sat 7:00 pm–12:00 am Sun 5:00 pm–11:00 pm Brunch Sun 11:00 am–1:30 pm Bar Wed 9:00 pm–12:00 am
  • Payment options
    AMEX, Cash not accepted, Discover, Mastercard, Visa
  • Dress code
    Business Casual
  • Private party facilities
    Please Email your request to reservations@chemistrychicago.com
  • Neighborhood
    Hyde Park
  • Parking details
    Private Lot
  • Additional
    Bar/Lounge, Beer, Cocktails, Counter Seating, Full Bar, Happy Hour, Non-Smoking, Private Room, Weekend Brunch, Wheelchair Access, Wine

Offers

  • 🔥 LIT Sunday Brunch Buffet 🔥

    1 - 12 people

    Multiple dates available
    Sun - 11:00 AM - 1:30 PM
    Join us on Sundays at either 11am or 1pm for our LIT Sunday Brunch Buffet - only $60 per person 🔥

Concierge
AI Beta

Our AI assistant, Concierge, is here to answer your questions about this restaurant.

Videos

Shared by creators who recently dined at this restaurant.

  • Profile image

    indulginginflavors

    🍴Dinner is served @chemistrychicago 🔥 • • • #chicagoblackrestaurantweek #chicagoblackownedbusiness #blackowned #chicagofoodie #chicagoeats #hydepark #eaterchicago #blackcontentcreators #eeeeeats #foodporn #foodgasm

Videos are powered by Seekeasy. How this content is generated

Reviews

OpenTable reviews from verified diners

Reviews from people who have dined at Chemistry.

4.6

4.6
(2450)
  • 4.5Food
  • 4.5Service
  • 4.7Ambience
  • 4.3Value

Noise • Moderate

Review summary

AI-generated from verified diner reviews
Chemistry offers an electrifying dining experience with "amazing food," "exceptional service," and a vibrant "atmosphere" ideal for celebrations. Guests rave about the "live music" and engaging entertainment. While some find it "a bit pricey," most agree it's "worth it" for the memorable ambiance and "top-tier" dining.
2,450 Reviews
  1. Evett Gold

    Houston21 reviews

    5.0

    Dined 1 day ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    The food was very good. We had the chicken and lamb chops. Both were served with mashed potatoes. They were real with real butter and milk! I had the lamb chops (4) cooked medium - 2 lemon and herb and 2 jerk. My favorite was the lemon herb. Jerk taste like Heinz 57 which I like but not on my lamb chops. The cocktails were but a little sweet. I think it was the peach nectar. I had club soda added. The popcorn appetizer was unique and tasty. I could have eaten an entire bowl. The decor… elegant and simply beautiful. The entertainer was very good. The decor and entertainment made the experience memorable. I recommend experiencing Chemistry while in Hyde Park - Chicago.

    Is this helpful?

  2. Lv

    Chicago1 review

    3.0

    Dined 3 days ago

    1. Overall 3
    2. Food 3
    3. Service 5
    4. Ambience 5
    I came here two years ago for My birthday and they had an amazing airline chicken it was so juicy and full of flavor but this time around we came in and it was sooo dry and lacked flavor leaving us highly disappointed….

    Is this helpful?

  3. Katherine

    Chicago1 review

    5.0

    Dined 6 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    I had the absolute great time it was my birthday and they celebrated me with great food, entertainment and great customer service. I will definitely revisit when I come back to Chicago

    Is this helpful?

  4. Kim

    St. Louis1 review

    4.0

    Dined 7 days ago

    1. Overall 4
    2. Food 5
    3. Service 4
    4. Ambience 5
    Extremely expensive and a bit over priced. A great place to be celebrated and appreciated. Great service and the vibes was amazing. Just way over priced.

    Is this helpful?

  5. Les

    Detroit4 reviews

    5.0

    Dined 7 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 4
    Staff was great, especially Jeremiah. We expect a nice dinner and ambiance and received so much more...pleasantly surprised!!! All the birthday/special occasions twists were great too!!!

    Is this helpful?

  6. Kendale

    Chicago2 reviews

    5.0

    Dined on October 29, 2026

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Everything was perfect from our server Kenny to the atmosphere and vibe of the whole place great place if you want a romantic experience or even just want to celebrate ur birthday and have fun overall 10/10 experience for me and my girl

    Is this helpful?

  7. Nikia

    St. Louis2 reviews

    5.0

    Dined on October 25, 2026

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    THIS PLACE IS THE BOMBBBB! We went here to celebrate our upcoming wedding 11/14/26! The staff were great! The food was great! The vibe was BOMB! The DJ was the best! What more can you ask for!

    Is this helpful?

  8. Nicole

    Houston1 review

    5.0

    Dined on October 25, 2026

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    The vibes, food, drinks, everything was amazing! We celebrated my boyfriend's birthday and they definitely made him feel special.

    Is this helpful?

  9. Makayla

    Louisville1 review

    5.0

    Dined on October 25, 2026

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    First Timer and It Was AMAZING! Service Was Great . Food Was Great . Atmosphere Was Great .

    Is this helpful?

  10. Yolanda

    San Francisco1 review

    3.0

    Dined on October 25, 2026

    1. Overall 3
    2. Food 4
    3. Service 5
    4. Ambience 5
    The service from Kenny was amazing and made an overall difference. Beautiful spot but the concept is for couples and not girls night out. We visited Chicago from Dallas as was excited to experience a black owned establishment. However, the bill and check was not accommodating or couldn’t be split. The lamb chop were seasoned and good choice. Need more vegan options. Two table seating not for groups or friends. Wish them the best! Good luck!

    1 person found this helpful

Dining areas

Additional information

  • Dining style
    Casual Dining
  • Price
    $31 to $50
  • Cuisines
    American
  • Hours of operation
    Mon, Tue, Thu 6:00 pm–10:30 pm Wed 6:30 pm–8:30 pm Sat 7:00 pm–12:00 am Sun 5:00 pm–11:00 pm Brunch Sun 11:00 am–1:30 pm Bar Wed 9:00 pm–12:00 am
  • Payment options
    AMEX, Cash not accepted, Discover, Mastercard, Visa
  • Dress code
    Business Casual
  • Private party facilities
    Please Email your request to reservations@chemistrychicago.com
  • Neighborhood
    Hyde Park
  • Parking details
    Private Lot
  • Additional
    Bar/Lounge, Beer, Cocktails, Counter Seating, Full Bar, Happy Hour, Non-Smoking, Private Room, Weekend Brunch, Wheelchair Access, Wine

FAQs

Sunday is a favourite, Sunday brunch (served 11:00 am–1:30 pm) draws repeated praise from guests for its vibe and food.

Guests commonly describe the portions as generous, one guest even called the Caesar salad “big enough for an entrée, ” and other diners note satisfying serving sizes.

Yes, Chemistry is frequently recommended for date nights and anniversaries, with guests praising its vibe, attentive service, and celebratory atmosphere; the listed dress code is Business Casual.

Chemistry gets busiest in the late-evening party hours, expect long waits and a club-like scene once entertainment ramps up, especially on weekend nights; earlier seatings (for example, before about 8:30 PM on a Saturday) feel more like a live-jazz set and tend to be less of a party.

Yes, for large parties (over 12) the restaurant asks you to email reservations@chemistrychicago.com to make arrangements, and many guests report leaving celebration notes on their reservations in advance.

Chemistry mixes a high‑end steakhouse with booming brunch energy and nightlife, expect showy, picture‑ready interiors, live bands and DJs, and an energetic, celebratory vibe that shifts from jazz‑leaning early evenings to full party mode later on.

Business casual is the guide, aim for neat, polished attire (think a collared shirt, nice top or dress) rather than athletic wear.

For a standout experience, plan for Sunday brunch (Chemistry’s brunch runs 11:00 am–1:30 pm), guests repeatedly praise the brunch’s food, vibe, and music. If you want live music or a nightclub‑style evening, Saturday nights are the place: arriving before ~8:30 pm tends toward a jazz feel, while after 9 pm it becomes more of a party scene.

How FAQ content is generated

  1. Home
  2. United States
  3. Chicago / Illinois
  4. Chicago
  5. Hyde Park

Make a reservation

A photo of Chemistry restaurant

Chemistry

4.6
$31 to $50
American
Hyde Park

Make a reservation

2 people
7:00 PM
Booked 62 times today
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Accessibility Statement
  • Cookie Preferences
Copyright © 2026 OpenTable Australia Level 22, 357 Collins Street, Melbourne, Victoria - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo