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Restaurants near Red Roof Inn Durham Duke University Medical Center

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220 restaurants available nearby

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A photo of Durham - M Sushi restaurant
1. Durham - M Sushi
4.9
Exceptional(3329)
$$$$
• Sushi • Durham
Booked 65 times today
M Sushi, the flagship of the acclaimed M Restaurants group by Chef Michael Lee, is the Triangle’s first dedicated sushi and seafood restaurant. Located in the heart of Downtown Durham, M Sushi sets the standard for exceptional sushi, Omakase, and seafood-driven cuisine. With a focus on fresh, high-quality ingredients and masterful execution, the menu showcases traditional Japanese techniques with innovative twists. Open for lunch and dinner, M Sushi delivers an unparalleled dining experience that continues to set the bar for sushi excellence. Experience the origins of M Restaurants at M Sushi.
A photo of Juju Durham restaurant
2. Juju Durham
4.9
Exceptional(2674)
$$$$
• Asian • Durham
Booked 43 times today
Juju serves up small plates with bold flavors, each prepared creatively with attention to tradition, whimsy, local integrity, and, of course, deliciousness. In addition to its extensive and delicious menu, Juju features a dynamic beverage program of hand-made cocktails, Sake selections and a well-chosen list of artisan wines and craft beers.
A photo of Vin Rouge restaurant
3. Vin Rouge
4.8
Exceptional(4748)
$$$$
• French • Durham
Booked 33 times today
Vin rouge is a French Bistro. We focus on classic preparations served in a true bistro atmosphere. We have beautiful patio and garden areas for those who prefer to dine outside. Please indicate your preference for dining inside or out. We look forward to cooking for you soon!
A photo of Little Bull restaurant
4. Little Bull
4.7
Exceptional(943)
$$$$
• Fusion / Eclectic • Durham
Booked 44 times today
Little Bull is sincere, nostalgic comfort food, inspired by the palates of first-generation immigrant kids. Pocho cuisine is not a gimmick. Like Oscar, it’s a little bull-headed, but with no bullshit. It means more than loaded terms like “New American” or “modern Mexican.” And it’s authentic to Chef’s personal experience.“American food is undefined. But it’s been designated to certain ideas and people. It’s actually evolving, as much as our landscape is a melting pot. As much as my own identity as a first-generation American and chef.”Pocho started as a term used by people in Mexico to poke fun at the “American” kids who speak Spanglish. At Little Bull, pocho cuisine showcases the evolution of being a chef in America, inspired by every immigrant and their growing influence on our food.
A photo of Nikos restaurant
5. Nikos
4.8
Exceptional(757)
$$$$
• Greek • Durham
Booked 31 times today
Nikos, a Michelin Recommended 2025 establishment, offers a treasure trove of authentic flavors distilled from Greece and the surrounding regions—spanning from the southern coast of Crete to the north of Mount Athos, and from the Ionian islands to the Aegean Sea. Under the culinary direction of celebrated Chef Douglas Rodriguez, we invite you to embark on a gastronomic journey that encompasses health, wisdom, dreams, passions, and the timeless pursuit of ideas that transcend boundaries. Experience a truly inspired Mediterranean dining event.Regular hours may be different during holidays weekend.
A photo of The Lenny 555 restaurant
6. The Lenny 555
4.2
Awesome(139)
$$$$
• Contemporary American • Durham
Booked 48 times today
The Lenny is a rooftop restaurant, cocktail bar, and event space held eleven stories high in Durham, NC. Nestled between the Durham Performing Arts Center (DPAC) and the Durham Bulls Baseball Stadium, you'll find a menu of freshly shucked oysters and filet mignon listed alongside an amazing Korean fried chicken sandwich and seasonal shareable flatbreads. Pair all of that with a stunning cocktail from our bar or share a bottle from our extensive wine list. Brunch takes the cake every weekend from 11-3pm with local DJs every Sunday. Our 180 degree view of the downtown Durham skyline is the perfect backdrop for any occasion. Follow us @thelenny555 to keep up with upcoming events and special menus.While it is beautiful and scenic, our outdoor dining space is not weather proof. In the event of inclement weather your reservation may be canceled. If poor weather is forecasted within 24 hrs of your reservation and you have not heard from us, we advise contacting the restaurant directly.
A photo of Seraphine restaurant
7. Seraphine
4.8
Exceptional(980)
$$$$
• Creole / Cajun / Southern • Durham
Booked 28 times today
Seraphine is on OpenTable! We look forward to seeing you!
A photo of Aaktun Coffee + Bar restaurant
8. Aaktun Coffee + Bar
4.7
Exceptional(320)
$$$$
• Latin American • Durham
Booked 22 times today
Our cozy cafe is a delightful haven where friends gather amidst the aroma of freshly brewed coffee, savoring delectable pastries and engaging in warm, leisurely conversations. Take a step into our dining room and allow us to whisk you away to a tropical paradise where contemporary tiki cocktails blend seamlessly with vibrant Latin American and Caribbean Flavors. Our culinary journey is guided by the talented Oscar Diaz, a two-time James Beard semi-finalist and our esteemed chef-owner.
A photo of Cucciolo Osteria Durham restaurant
9. Cucciolo Osteria Durham
4.7
Exceptional(1895)
$$$$
• Italian • Durham
Booked 32 times today
Cousins Jimmy and Julian Kim welcome you to Cucciolo Osteria Durham! A sister restaurant to the original Cucciolo Osteria in Seoul, Korea, offering modern Italian cuisine with a twist.We are located in the same building as the Amtrak train station, just opposite side, next to West End Wine Bar.
A photo of Parizade restaurant
10. Parizade
4.7
Exceptional(3483)
$$$$
• Mediterranean • Durham
Booked 18 times today
Parizade is Mediterranean inspired culinary creations. A vast open kitchen spans the length of the restaurant. Surreal art by Henryk Fantazos adorns the walls and ceiling. Parizade is truly the crowning jewel of Giorgios Hospitality Group. *Large parties, please call the restaurant at 919-286-9712*

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Dining near Red Roof Inn Durham Duke University Medical Center at a glance

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Most popular restaurant

popular restaurant

Durham - M Sushi

4.9

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Discover local gems

Exceptional reviews

Most popular cuisine

popular cuisine

American

Average check amount

$30 and under

See what locals rave about

From verified diners like you
From verified diners like you
  • Mark
    Raleigh / Durham / Chapel Hill •14 reviews
    5.0
    Dined 3 days ago
    Excellent food and fantastic service The bar manager Patrick gives great suggestions and tailors drinks to make the experience perfect. My partner liked our server Margaret Rose so much we cancelled reservations for other restaurants and ate here three days in a row. 2 dinners and a brunch. All were fantastic!!
    More info
    Nikos$$$$• Greek• Durham
    •
    4.8
  • Nick
    Raleigh / Durham / Chapel Hill •14 reviews
    5.0
    Dined 4 days ago
    The entire experience was nothing short of excellent. This place has it all. The food, the service, and the ambience blend perfectly together for an outstanding night out
    More info
    Vin Rouge$$$$• French• Durham
    •
    4.8
  • Justin
    Raleigh / Durham / Chapel Hill •4 reviews
    5.0
    Dined 4 days ago
    What an amazing dinner! It was my wife's birthday so we stopped in for some sushi this weekend. Narga guided us through a tasting of all of the in-house sodas, in addition to recommending some of the newer smaller plates. We settled on the crudo, eel bao, and smoked cod to start (highly recommend every one of these dishes!). Afterwards, we settled in for a light omakase and ngiri sampler. Every cut of protein was absolutely divine. Narga even treated my wife to a complementary prosecco to close out the night due to us celebrating her birthday. 11/10 experience. Thanks to Narga, Tay, and the crew at M for making my wife's birthday unforgettable!
    More info
    Durham - M Sushi$$$$• Sushi• Durham
    •
    4.9
  • PeterGold
    New York City •61 reviews
    5.0
    Dined on Jul 6, 2026
    Innovative and excellently prepared and delivered. You Must try this restaurant. Super impressed.
    More info
    Little Bull$$$$• Fusion / Eclectic• Durham
    •
    4.7
  • Stephanie
    Raleigh / Durham / Chapel Hill •8 reviews
    5.0
    Dined on Jul 6, 2026
    The food was spectacular! We sampled almost a dozen small plates across our table avd every one was simply delicious!!!
    More info
    Juju Durham$$$$• Asian• Durham
    •
    4.9

Discover best restaurants near Red Roof Inn Durham Duke University Medical Center

Discover a variety of dining options near the Red Roof Inn Durham Duke University Medical Center, the perfect base for both leisure and healthcare visitors. Where to Eat Near Red Roof Inn Durham Duke University Medical Center? The nearby dining scene offers vibrant and varied experiences, making it easy to find a meal to satisfy any craving. You'll find casual dining spots serving up everything from Asian-inspired small plates bursting with flavor to nostalgic fusion dishes that reflect the melting-pot culture of American cuisine. For fans of classic fare, you can indulge in Italian dishes showcasing fresh ingredients and modern twists. Complemented by dynamic beverage programs, these eateries create inviting atmospheres perfect for enjoying good food with friends or family. Whether you're in the mood for comforting favorites or modern culinary twists, there’s something for everyone right around the corner.

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