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Restaurants near Residence Inn by Marriott Durham Duke University Medical Center Area

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230 restaurants available nearby

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A photo of Nikos restaurant
1. Nikos
4.7
Exceptional(810)
$$$$
• Greek • Durham
Booked 64 times today
Nikos, a Michelin Recommended 2025 establishment, offers a treasure trove of authentic flavors distilled from Greece and the surrounding regions—spanning from the southern coast of Crete to the north of Mount Athos, and from the Ionian islands to the Aegean Sea. Under the culinary direction of celebrated Chef Douglas Rodriguez, we invite you to embark on a gastronomic journey that encompasses health, wisdom, dreams, passions, and the timeless pursuit of ideas that transcend boundaries. Experience a truly inspired Mediterranean dining event.Regular hours may be different during holidays weekend.
A photo of Emmy Squared - Durham restaurant
2. Emmy Squared - Durham
4.8
Exceptional(191)
$$$$
• Pizzeria • Durham
Booked 25 times today
Emmy Squared Pizza: Durham offers North Carolina's best Detroit-style pizza, alongside craveable bites and a full bar featuring specialty cocktails. Join us for Happy Hour Monday–Wednesday all day. The top choice for crafted pizza in North Carolina.In 2014, Emily and Matt opened their first restaurant in Clinton Hill, Brooklyn, with a goal to create quality pies. A trip to Detroit changed everything: they loved the local style, the crispy cheese edge, airy dough, and bold red sauce. They knew pairing this base with chef-inspired toppings would be special.Back in Brooklyn, they began experimenting with organic flour, aged cheeses, fresh tomatoes, and combinations like truffle/mushrooms or pesto/Calabrian chilies, perfecting that crave-worthy cheese crust. In 2016, they unveiled their Detroit-style take with Emmy Squared Pizza. They remain committed to crafting the country's most thoughtful pizzas. We hope you enjoy them!Detroit-Style Soul, Brooklyn Born.
A photo of Little Bull restaurant
3. Little Bull
4.7
Exceptional(1088)
$$$$
• Fusion / Eclectic • Durham
Booked 48 times today
Little Bull is sincere, nostalgic comfort food, inspired by the palates of first-generation immigrant kids. Pocho cuisine is not a gimmick. Like Oscar, it’s a little bull-headed, but with no bullshit. It means more than loaded terms like “New American” or “modern Mexican.” And it’s authentic to Chef’s personal experience.“American food is undefined. But it’s been designated to certain ideas and people. It’s actually evolving, as much as our landscape is a melting pot. As much as my own identity as a first-generation American and chef.”Pocho started as a term used by people in Mexico to poke fun at the “American” kids who speak Spanglish. At Little Bull, pocho cuisine showcases the evolution of being a chef in America, inspired by every immigrant and their growing influence on our food.
A photo of Durham - M Sushi restaurant
4. Durham - M Sushi
4.9
Exceptional(3380)
$$$$
• Sushi • Durham
Booked 50 times today
M Sushi, the flagship of the acclaimed M Restaurants group by Chef Michael Lee, is the Triangle’s first dedicated sushi and seafood restaurant. Located in the heart of Downtown Durham, M Sushi sets the standard for exceptional sushi, Omakase, and seafood-driven cuisine. With a focus on fresh, high-quality ingredients and masterful execution, the menu showcases traditional Japanese techniques with innovative twists. Open for lunch and dinner, M Sushi delivers an unparalleled dining experience that continues to set the bar for sushi excellence. Experience the origins of M Restaurants at M Sushi.
A photo of Juju Durham restaurant
5. Juju Durham
4.8
Exceptional(2738)
$$$$
• Asian • Durham
Booked 42 times today
Juju serves up small plates with bold flavors, each prepared creatively with attention to tradition, whimsy, local integrity, and, of course, deliciousness. In addition to its extensive and delicious menu, Juju features a dynamic beverage program of hand-made cocktails, Sake selections and a well-chosen list of artisan wines and craft beers.
A photo of Vin Rouge restaurant
6. Vin Rouge
4.8
Exceptional(4791)
$$$$
• French • Durham
Booked 35 times today
Vin rouge is a French Bistro. We focus on classic preparations served in a true bistro atmosphere. We have beautiful patio and garden areas for those who prefer to dine outside. Please indicate your preference for dining inside or out. We look forward to cooking for you soon!
A photo of Seraphine restaurant
7. Seraphine
4.8
Exceptional(1082)
$$$$
• Creole / Cajun / Southern • Durham
Booked 56 times today
Seraphine is on OpenTable! We look forward to seeing you!
A photo of Cucciolo Osteria Durham restaurant
8. Cucciolo Osteria Durham
4.7
Exceptional(1942)
$$$$
• Italian • Durham
Booked 36 times today
Cousins Jimmy and Julian Kim welcome you to Cucciolo Osteria Durham! A sister restaurant to the original Cucciolo Osteria in Seoul, Korea, offering modern Italian cuisine with a twist.We are located in the same building as the Amtrak train station, just opposite side, next to West End Wine Bar.
A photo of NanaSteak restaurant
9. NanaSteak
4.8
Exceptional(3050)
$$$$
• Steakhouse • Durham
Booked 34 times today
NanaSteak offers high-energy upscale dining at its finest. Enjoy drinks and appetizers with friends at the beautiful and well appointed bar or dine from a menu full of local North Carolina fare. The award wining wine list offers many unique and interesting selections to compliment any meal. With an impeccable attention to detail, this is the perfect backdrop for an extraordinary evening. In short, NanaSteak is more than just Durham's finest steakhouse.
A photo of M Hansik restaurant
10. M Hansik
4.7
Exceptional(86)
$$$$
• Korean • Durham
Booked 25 times today
At M Hansik, we offer a modern take on traditional Korean cuisine - rooted in heritage, reimagined with creativity. We invite you to keep an open mind and enjoy our playful interpretations of classic Korean dishes.

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Dining near Residence Inn by Marriott Durham Duke University Medical Center Area at a glance

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Most popular restaurant

popular restaurant

Dame's Chicken & Waffles

5

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Discover local gems

Exceptional reviews

Most popular cuisine

popular cuisine

American

Average check amount

$30 and under

See what locals rave about

From verified diners like you
From verified diners like you
  • Diane
    Washington, D.C. Area •10 reviews
    5.0
    Dined 2 days ago
    The small plates were tasty and filling. My husband and I ordered 3 of them and made a dinner of them. The cocktails hit the spot.
    More info
    Juju Durham$$$$• Asian• Durham
    •
    4.8
  • Robert
    Raleigh / Durham / Chapel Hill •177 reviews
    4.0
    Dined 2 days ago
    Loved the flounder, tomato/cucumber salad and zucchini cakes. Jonathan is an excellent bartender.
    More info
    Nikos$$$$• Greek• Durham
    •
    4.7
  • Sallie
    Raleigh / Durham / Chapel Hill •3 reviews
    5.0
    Dined 3 days ago
    Fabulous from start to finish - really delicious and imaginative dishes Service is always stellar. Wonderful cocktails. A real treat - feels very special and welcoming.
    More info
    Little Bull$$$$• Fusion / Eclectic• Durham
    •
    4.7
  • Nakia
    Raleigh / Durham / Chapel Hill •4 reviews
    4.0
    Dined on Oct 30, 2026
    The food and atmosphere made for a really nice, laid-back dining experience. Finding the restaurant was a little tricky at first, but the hostess was friendly and helped guide us in the right direction. The prices are definitely on the higher side, but the food we ordered was well-prepared, fresh, and full of flavor. Our server was just okay, but the overall experience more than made up for it. Despite a few minor hiccups, we'd absolutely come back. It's a great spot for a relaxed date night, especially if you're looking for good sushi and a chill atmosphere!
    More info
    Durham - M Sushi$$$$• Sushi• Durham
    •
    4.9
  • CRAIG
    Atlanta •1 review
    5.0
    Dined on Oct 9, 2026
    We loved the one in Alexandrai, VA so were happy to see one in NC. Their Gluten Free pizza is amazing (expensive, but amazing).
    More info
    Emmy Squared - Durham$$$$• Pizzeria• Durham
    •
    4.8

Discover best restaurants near Residence Inn by Marriott Durham Duke University Medical Center Area

Experience comfort and convenience at the Residence Inn by Marriott Durham Duke University Medical Center Area, a perfect spot for both business and leisure travelers. Where to Eat Near Residence Inn by Marriott Durham Duke University Medical Center Area? The dining scene nearby is wonderfully diverse, catering to a variety of tastes. Enjoy Mediterranean delights with fresh seafood and artisanal creations, or dive into hearty American comfort food featuring deliciously crafted pizzas and burgers. For those looking to explore international flavors, Greek cuisine offers vibrant dishes that capture the essence of the Mediterranean. The vibrant atmosphere and culinary offerings make for an enjoyable dining experience, whether you’re looking for a casual meal or a more elegant evening out. Discover the perfect spot to satisfy your cravings near the Residence Inn by Marriott.

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